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rabbit polyclonal anti ca v 2 1 α 1a antibody  (Alomone Labs)


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    Structured Review

    Alomone Labs rabbit polyclonal anti ca v 2 1 α 1a antibody
    Generation of conditional Cacna1a Purkinje cell-specific knockout mice. a Schematic representation of the genomic structure of the relevant part of the floxed and recombined Cacna1a alleles. Black boxes indicate exons ( E ). Triangles indicate the position of loxP sites. Arrows indicate the position of the primers used for the RT-PCR. b RT-PCR of cerebellar RNA amplifies a 580-bp product from the non-recombined Cacna1a transcript and a 490-bp product from transcripts that lack exon 4. c – f Anti-Ca V 2.1-α 1A immunostaining in cerebellar sections of P30 WT ( c , e ) and PCα1KO ( d , f ) mice. CN cerebellar nuclei, G granule cell layer, M molecular layer, PC Purkinje cell layer, WM white matter. Roman numbers indicate the cerebellar lobules
    Rabbit Polyclonal Anti Ca V 2 1 α 1a Antibody, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 94/100, based on 57 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/rabbit+polyclonal+anti+ca+v+2+1+%CE%B1+1a+antibody/pmc03311848-51-24-33?v=Alomone+Labs
    Average 94 stars, based on 57 article reviews
    rabbit polyclonal anti ca v 2 1 α 1a antibody - by Bioz Stars, 2026-07
    94/100 stars

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    1) Product Images from "Purkinje Cell-Specific Ablation of Ca V 2.1 Channels is Sufficient to Cause Cerebellar Ataxia in Mice"

    Article Title: Purkinje Cell-Specific Ablation of Ca V 2.1 Channels is Sufficient to Cause Cerebellar Ataxia in Mice

    Journal: Cerebellum (London, England)

    doi: 10.1007/s12311-011-0302-1

    Generation of conditional Cacna1a Purkinje cell-specific knockout mice. a Schematic representation of the genomic structure of the relevant part of the floxed and recombined Cacna1a alleles. Black boxes indicate exons ( E ). Triangles indicate the position of loxP sites. Arrows indicate the position of the primers used for the RT-PCR. b RT-PCR of cerebellar RNA amplifies a 580-bp product from the non-recombined Cacna1a transcript and a 490-bp product from transcripts that lack exon 4. c – f Anti-Ca V 2.1-α 1A immunostaining in cerebellar sections of P30 WT ( c , e ) and PCα1KO ( d , f ) mice. CN cerebellar nuclei, G granule cell layer, M molecular layer, PC Purkinje cell layer, WM white matter. Roman numbers indicate the cerebellar lobules
    Figure Legend Snippet: Generation of conditional Cacna1a Purkinje cell-specific knockout mice. a Schematic representation of the genomic structure of the relevant part of the floxed and recombined Cacna1a alleles. Black boxes indicate exons ( E ). Triangles indicate the position of loxP sites. Arrows indicate the position of the primers used for the RT-PCR. b RT-PCR of cerebellar RNA amplifies a 580-bp product from the non-recombined Cacna1a transcript and a 490-bp product from transcripts that lack exon 4. c – f Anti-Ca V 2.1-α 1A immunostaining in cerebellar sections of P30 WT ( c , e ) and PCα1KO ( d , f ) mice. CN cerebellar nuclei, G granule cell layer, M molecular layer, PC Purkinje cell layer, WM white matter. Roman numbers indicate the cerebellar lobules

    Techniques Used: Knock-Out, Reverse Transcription Polymerase Chain Reaction, Immunostaining



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    94
    Alomone Labs rabbit polyclonal anti ca v 2 1 α 1a antibody
    Generation of conditional Cacna1a Purkinje cell-specific knockout mice. a Schematic representation of the genomic structure of the relevant part of the floxed and recombined Cacna1a alleles. Black boxes indicate exons ( E ). Triangles indicate the position of loxP sites. Arrows indicate the position of the primers used for the RT-PCR. b RT-PCR of cerebellar RNA amplifies a 580-bp product from the non-recombined Cacna1a transcript and a 490-bp product from transcripts that lack exon 4. c – f Anti-Ca V 2.1-α 1A immunostaining in cerebellar sections of P30 WT ( c , e ) and PCα1KO ( d , f ) mice. CN cerebellar nuclei, G granule cell layer, M molecular layer, PC Purkinje cell layer, WM white matter. Roman numbers indicate the cerebellar lobules
    Rabbit Polyclonal Anti Ca V 2 1 α 1a Antibody, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/rabbit+polyclonal+anti+ca+v+2+1+%CE%B1+1a+antibody/pmc03311848-51-24-33?v=Alomone+Labs
    Average 94 stars, based on 1 article reviews
    rabbit polyclonal anti ca v 2 1 α 1a antibody - by Bioz Stars, 2026-07
    94/100 stars
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    Generation of conditional Cacna1a Purkinje cell-specific knockout mice. a Schematic representation of the genomic structure of the relevant part of the floxed and recombined Cacna1a alleles. Black boxes indicate exons ( E ). Triangles indicate the position of loxP sites. Arrows indicate the position of the primers used for the RT-PCR. b RT-PCR of cerebellar RNA amplifies a 580-bp product from the non-recombined Cacna1a transcript and a 490-bp product from transcripts that lack exon 4. c – f Anti-Ca V 2.1-α 1A immunostaining in cerebellar sections of P30 WT ( c , e ) and PCα1KO ( d , f ) mice. CN cerebellar nuclei, G granule cell layer, M molecular layer, PC Purkinje cell layer, WM white matter. Roman numbers indicate the cerebellar lobules

    Journal: Cerebellum (London, England)

    Article Title: Purkinje Cell-Specific Ablation of Ca V 2.1 Channels is Sufficient to Cause Cerebellar Ataxia in Mice

    doi: 10.1007/s12311-011-0302-1

    Figure Lengend Snippet: Generation of conditional Cacna1a Purkinje cell-specific knockout mice. a Schematic representation of the genomic structure of the relevant part of the floxed and recombined Cacna1a alleles. Black boxes indicate exons ( E ). Triangles indicate the position of loxP sites. Arrows indicate the position of the primers used for the RT-PCR. b RT-PCR of cerebellar RNA amplifies a 580-bp product from the non-recombined Cacna1a transcript and a 490-bp product from transcripts that lack exon 4. c – f Anti-Ca V 2.1-α 1A immunostaining in cerebellar sections of P30 WT ( c , e ) and PCα1KO ( d , f ) mice. CN cerebellar nuclei, G granule cell layer, M molecular layer, PC Purkinje cell layer, WM white matter. Roman numbers indicate the cerebellar lobules

    Article Snippet: Sections were incubated in 10% heat-inactivated normal horse serum (NHS) with 0.5% Triton-X100 in TBS, for 2 h and then incubated either with primary rabbit polyclonal anti-Ca V 2.1-α 1A antibody (ACC-001, 1:100; Alomone Labs, Jerusalem, Israel), or with rabbit polyclonal anti-Calbindin antibody (CB38, 1:10,000; SWANT, Bellinzona, Switzerland) diluted in 1% NHS with 2% heat-inactivated fetal calf serum and 0.4% Triton-X100 in TBS at 4°C.

    Techniques: Knock-Out, Reverse Transcription Polymerase Chain Reaction, Immunostaining